Adidas Product Life Cycle

Adidas Product Life Cycle The product life cycle concept may apply to our product, Adidas Deep Energy Deodorant. The product life cycle concept helps our marketing managers to plan marketing strategies to address the challenges that our products are likely to face. Products life cycle can be divided into several stages which include introduction stage, growth stage, maturity stage and decline stage. Introduction stage shows small or even no sales and the company make no profit. When the Adidas men deep energy deodorant is introduced, sales will be low until customers become aware of the product and its benefits. This stage involves lots of research, expenditure and planning are required. Advertising costs of our deodorants product are high during this stage in order to quickly increase customer awareness of the product and to target the early adopters. During the introduction stage, we are expecting to incur additional costs related with the initial distribution of the product. These higher costs fixed with a low sales normally make the introduction stage a period of negative profits. Growth stage During growth stage, the sales increase due to attracting more competition into the market. Similar products starts come up and we have to focus on competitive advantages which can be price reduction, value added features or some other innovations. Profits rise due to an increase in output and perhaps better prices. At this stage, it is cheaper for Adidas to invest in enhance their market share as well as enjoying the overall growth of the market. Maturity stage In the maturity stage, sales of our product growth slow and generic competition appear. We may enhance our deodorant product features to differentiate the product. The selling price may start to erode under competitive price. In this stage, competition is strong as companies contest to maintain their market share. The Maturity Stage is the time when most profit is earned by the market as a whole. Some expenditure on research and development is likely to be controlled to our deodorant product modification and improvement and to improve production efficiency and quality. Decline stage In the Decline Stage, the market is reducing, decreasing the overall total of profit that can be shared with other competitors. Decline stage appear for some reasons the sales of our deodorant product start decreasing, the reasons can be some new and better choices or diminishing demand. At this stage, we have to manage our product carefully. It may be likely to cut out some production cost, to transfer production to a cheaper facility, sell the product into other cheaper markets. Core Product Adidas Deep Energy deodorants for Men provide the consumers the fresh, woody fragrance. This deep energy deodorant for men is alcohol-based, and provides excellent anti-bacterial formulation to consumers. It helps in keeping the under-arms fresh all day long, and also facilitate in reducing perspiration levels. In addition, it helps in deactivate the bacteria, and in turn ensuring zero body odors. This deodorant provides great protection against sweat and odor. This range has been developed with athletes in mind to give the best possible protection against sweat and odor. It also reducing ability of bacteria to breed thus gets rid of a sweat smell. Actual product The brand name of our product is Adidas Men Deodorant Clear Stick, Deep Energy. The selling price of it is RM8.90. Packaging design plays a crucial role in helping to communicate the image of the product. Black is a color choice for the packaging. They also used a hard container to emphasize the sport spirit in the product. 3 oz and 85g of a bottle with a slanted black plastic flip-top lid design to the top of it. It is developed for athletes, unique energizing fragrance, and 24 hours fresh power remain. The advertisement for the Adidas deodorant features the three guys playing basketball under the shining hot sun. Mysteriously their faces are not shown, nor the colors that they wear and remain secret. There is just the image of them playing basketball. With the presence of the fading orange background, it seems as if these guys have been playing all day. The color design of the advertisement is very dull. In the middle through the advertisement, on the right hand side, there is a picture of the Adidas deep energy deodorants that the buyer can choose from. Augmented product Things considered part of the augmented product include guarantee, warranty, customer service, accessibility as well as complementary product. Guarantee offers an assurance of the product will perform up to expectations and if not the company marketing the product will support the customers decision to replace, repaired or return for a refund. Warranty provides customers the protection that often extends past the guarantee period to cover repair or replacement of our deodorants product. Customer Service consists of extra services that support the needs of customers including offering training and help using telephone or online. Thus, customers of our product can solve their problem by using these. Complementary Products is the value of some product purchases can be enhanced with add-on products, such as things that make the main product easier to use. For instance, small little cover bag gift with the deodorant which consumers can carry easily. Improves styling or offers functionality which will attract more customers to buy our deodorants product. Accessibility is how customers obtain the product can affect its perceived value depending on how easy it is to obtain, the speed at which it can be obtained, and the possibility its available when needed. We can supply our deodorant products to those convenience stores such as Guardian, Watson, 7-eleven, and supermarkets and so on. So that customers could obtain our deodorants product as easy and available when needed.

Mechanism of Transfer in Gene Therapy Essay examples -- Gene Therapy

Mechanism of Transfer in Gene Therapy Abstract: Gene therapy is the transfer of â€Å"normal† genes into the body to replace defective or undesired genes. The transfer may be in somatic or germline cells and may take place in vivo or in vitro. The DNA may be inserted in a retrovirus, adenovirus, adeno-associated virus, herpes simplex virus, or liposome, or it may be naked DNA. The vector travels to a target cell and inserts the gene, which goes to the host cell’s nucleus and may integrate into the genome. In cells with dominant negative genes, resulting protein must be prevented from translation or transcription using oligonucleotides or antisense technology. Though many obstacles delay the development of gene therapy, this new field will surely improve the future of medicine. Mechanism of Transfer in Gene Therapy Gene therapy is a method of replacing defective or undesired genes in the body with â€Å"normal† genes. A vector is re-engineered to deliver the gene to a target cell. Then the gene is transferred to the cell’s nucleus and must be activated in order to function. The gene must be integrated into the cell’s genome in order for it to continue to function and be replicated. Side effects are possible because the vector may be detected as a foreign substance by the body’s immune system. Gene therapy may take place either in vivo or in vitro, the transfer may be in either somatic or germline cells, and a variety of viral and non-viral vectors may be used. In vivo gene therapy is done inside a living organism. This is accomplished by inhalation, oral administration, intramuscular injection, or intravenous administration (Brooks, 24). Currently, most in vivo experiments have taken place in animals other than humans. Most gen... ...ocated, ensure that gene therapy will be a revolutionary aspect of medicine’s future. Bibliography Brooks, Gavin. Gene Therapy: The use of DNA as a drug. London: Pharmaceutical Press, 2002. â€Å"Gene Therapy.† Human Genome Project Information. 18 November 2005. U.S. Department of Energy and the National Institutes of Health. 28 July 2007. â€Å"Gene Therapy: Molecular Bandage?† Learn.Genetics. 2007. The University of Utah, Genetic Science Learning Center. 28 July 2007. Januario E. Castro, Thomas J. Kipps. â€Å"Chapter 26. Principles of Gene Transfer for Therapy.† Williams Hematology, 7th Edition. United States of America: The McGraw-Hill Companies, Inc., 2006. 28 July, 2007.

Bt Corn

Research Question â€Å"Evaluation of the commercialization of Bt-Corn breeds: how it is both economically efficient and overall beneficial for the environment. † Abstract This paper discusses and evaluates both the negative and positive aspects and raised controversial issues regarding Bt-Corn, a transgenic maize developed through genetic engineering and biotechnology methods, and will finally conclude that the commercialization of Bt-Corn breeds for the past 14 years have been both economically advantageous and beneficial for the environment.The purpose of this paper is to further educate and inform the general audience regarding issues relating with genetically modified organisms and will try to disprove negative speculation and ambiguity with statistical data and experimental evidence. Introduction Recent development and advances in the field of biotechnology and genetic engineering has enabled scientists today to improve crop varieties through alteration of their most fun damental building blocks, their DNA.These alterations of the genetic material allow scientists and researchers to develop ‘new species’ and breeds of organisms which posses certain altered favored traits, which would not otherwise naturally exist in the organism. (Peairs, 2007) However, there is much ambiguity and controversies surrounding the whole field of genetic engineering of organisms and their commercialization.Bt-corn, a breed of transgenic maize whose genetic material has been altered to include the ability to produce a certain toxin that has specific insecticidal property against pests, has been commercialized now for several years in the US and also in several other countries such as Canada, Germany, Spain, Argentina, Honduras, South Africa and the Philippines. (Wu, 2006) The prefix ‘Bt’ from Bt-Corn originates from Bacillus thuringiensis (Bt), a species of soil bacterium that produces the insecticidal crystal protein or delta endotoxins, toxins that kill crop pests.Genetic engineering has allowed scientists to take the single gene that controls the production of the delta endotoxins from Bt, create a modified version of it and synthesize it with the DNA of selected corn species using recombinant DNA technology. This new set of ‘genetic code’ allows the plant to produce the delta endotoxins by itself; hence it is able to repel crop pests by itself. This newly acquired attribute is like a miracle for farmers, not just corn farmers since the insecticidal attribute of ‘Bt’ has also been implemented in several other crops such as Bt-potatoes and Bt-sweet corn.However, there have been several issues raised against the commercialization of Bt-corn in recent years due to investigations, which reveals how Bt-corn pollen proves to be lethal to other species of organisms that are not considered as pests. (Peairs, 2007) This paper will discuss, evaluate and finally demonstrate how the commercialization of Bt- Corn breeds is overall both economically efficient and beneficial for the environment through the following points: * Origins of Bt and Bt-Corn * Mode of action of Bt toxins Economical and environmental advantages of Bt-Corn * FDA regulations on genetically modified organisms * Controversies and issues raised * Evaluation Origins of Bt and Bt-Corn As previously stated above, Bt-Corn is a breed of transgenic maize whose genetic material have been altered and combined with the insecticidal crystal protein-producing trait of the common naturally occurring soil bacterium, Bacillus thuringiensis. Shigetane Ishiwata, a Japanese biologist, was the first to discover Bacillus thuringiensis (Bt) in 1901.However, it was not until Ernst Berliner rediscovered it in 1911 in Thuringia, Germany, that the bacterium was named Bacillus thuringiensis. In 1938 a French company started commercially producing the combination of the bacterium and its toxin crystals as a pesticide, calling it Sporeine, and in the 1950’s American organic farmers started using Bt on their crops as a way to control pest. (Aroian) As research methods improved (1960’s) and new Bt species were found producing thousands of other specific toxic proteins, more and more farmers started to use Bt.However, it was not until advancements in genetics and genetic engineering in the 1990’s that researchers were able to detect and isolate the specific genes that trigger production of the toxins and transfer it into certain species of crops, such as Bt-Corn. The first Bt crop that was registered with the USEPA (United States Environmental Protection Agency), which allowed for its commercialization, is the Bt-Corn. (Aroian) In 2004, Bt-Corn comprises more than ? of the total acres of cornfields in the United States itself. Wu, 2006) According to Clive James, the chair of the ISAAA (International Service for the Acquisition of Agri-biotech Applications), today (2002) the total Bt-Corn fields in the wo rld approximates to 25 million acres. (James, 2002) Mode of actions of Bt toxins Bacillus thuringiensis produces certain proteins, categorized as crystal proteins, which are very specific, well known for its ability to target and inhibit specific metabolic processes of certain species of organisms, mainly insects.Investigations have revealed that most of these insecticidal crystal proteins, when activated (when they come into contact with their specific host), attaches itself to the epithelium cells of the gut of the insects and causes the generation of pores in the cell membranes. These pores in the membranes of the epithelium cells, outermost cells that line the surfaces of structures, such as the gut, of organisms, disrupts the osmotic balance of the cells, causing them to swell and lyse. (Hofte, 1989)In simpler terms, basically these proteins (toxins) cause imbalance of water absorption (osmotic imbalance) in the cells of the ‘organs’ of specific insects, which caus es these cells to swell and break (lyse). They are also very specific and selective on the species of insects they are able to affect, making Bt toxins potent in eradicating pests while being relatively harmless towards other organisms. There is substantial evidence that the toxins (insecticidal crystal proteins) are not harmful to human health nor are they detrimental for the health of vertebrates (mammals, reptiles, amphibians, birds, bony fish and sharks).According to Peairs, these toxins are considered to be very selective and very safe for humans and non-targeted organisms when compared to the most conventional and common pesticides used nowadays since they only attack certain groups of insects. (Peairs, 2007) Economical and environmental advantages of Bt-Corn It has been several years now, more than a decade, since the commercialization of Bt-Corn breeds and now more than ever, we are able to see statistical data and actual evidence that overall, using Bt-Corn is both economic ally efficient and beneficial for the environment.Economic advantages of Bt-Corn According to a study by Brookes, there have been substantial net economic benefits at the farms, totaling up to $5 billion in 2005 and $27 billion during the first decade (1996-2005) of the commercialization of genetically engineered crops. For the genetically engineered maize species, including Bt-Corn and other forms of genetically modified corn, boosted farm incomes by over $3. 1 billion since 1996. In the United States alone genetically modified maize crop income benefits accumulates to a little under $2. 3 billion, which is about 88% of the world GM maize crop income. (Brookes, 2006) The main reason for its economic advantage is its ability to produce higher yields of the same, or even better, quality of produce compared to ‘organic’ corn because two reasons. The first reason is that since pests are not lured to the crop, they unhindered and are able to flourish and produce more yields . The second reason is that the ability to self-produce insecticidal toxins allows farmers to cut down costs to maintain the crop since they do not have to purchase massive amounts of pesticide.This also means that less time will be spent on crop walking and the application of pesticides and herbicides, less usage of energy associated with less spraying, savings in costs of machinery and machinery usage (from less spraying and reduced harvest times) and also the unseen benefits in the health and safety of farm workers that is caused by handling pesticides. (Brookes, 2006) Environmental advantages of Bt-Corn The usage of Bt-Corn allows farmers to stop the usage of environmentally hazardous chemicals, may it be pesticides or herbicides.Overall between the years 1996 and 2005, GM crops have caused the net reduction in the environmental impact on the cropping area by 15. 3% while the total volume of active ingredient usage has also been reduced by 7%. Specifically in the GM maize sector there have been a net reduction in the environmental impact on the cropping area by 4. 6% through the reduction of pesticide usage and another net decrease in 4% in the environmental impact through the usage of more environmentally benign herbicides. Brookes, 2006) There has also been a decrease in greenhouse gasses emission; excess greenhouse gasses emission is a factor contributing to global warming. Brookes states in his article, that the two main reasons for the decrease in green house gasses emission is due to two factors. The first being reduced fuel usage from the less frequent need of using pesticides and herbicides applications (machinery used for spraying). From 1996 to 2005, it is estimated that there has been a reduction in carbon dioxide emission of 4,613 million kg, calculated from the reduced fuel usage of 1,679 liters.In comparison, the permanent carbon dioxide savings from reduced fuel usage from 1996 to 2005 by planting GM crops is equivalent to the removal of 2. 05 million cars from the road for one year, assuming that a car does an average of 15,000 km per year, producing 2,250 kg of CO2 per year based on the fact that an average family car produces 150 grams of CO2 every km. (Brookes, 2006) FDA regulations on genetically modified organisms With the development in genetic engineering and biotechnology there is urgency and a need to both control and oversee products and methods used, especially relating with food products.The Food and Drug Administration (FDA), the Environmental Protection Agency (EPA) and United States Department of Agriculture (USDA) are the three main supervisors of genetically modified foods. The FDA, the official government agency in charge of regulating food, drug and cosmetic laws and ensuring safety of food (other than meat), food additives, medicines, medical devices, veterinary drugs, cosmetics and genetically modified food products, plays the major role in the actual ‘screening’ of products that are available for the public.The FDA categorizes genetically modified food products under the ‘GRAS’ list; the GRAS list comprise of products that are ‘generally recognized as safe’, which demands the manufacturers to be responsible for the safety of their own products, allowing them to place products into the market without pre-approval of the FDA because whole foods are GRAS. Whole foods are foods that are unprocessed or unrefined such as unprocessed meat, poultry and fish, fruits and vegetables, and non-homogenized milk (basically unprocessed milk; straight from the animal).The manufacturer bears responsibility for ensuring the product is not adulterated or misbranded. However if there is proof that the product is adulterated, or detrimental to human health (animal health for animal products), then the products may be taken back from the market and the manufacturer may be prosecuted. (Gertsberg, 2009) Controversies and issues raised The development and conti nuation of research in the whole issue regarding genetic engineering of any organisms itself raises much issues.However, most of the issues raised within the field of genetically modified organisms (GMOs) are issues regarding perspective and ethics, since there is much fear and ambiguity that most people feel when they think and speak about this issue. Controversies with genetic engineering There are not enough, if there are any, substantial, academic, plain physical experimental proof that genetically modified organisms are hazardous to both the health of humans and the environment.The main issues raised regarding GMOs are that there is a risk there new allergens will arise from the ‘unknown’ effects of combining different DNA sequences with each other, increased toxicity levels in organisms do to a faster metabolism, the possibility of unwanted/unintended gene transfer between different species, loss of biodiversity and basically unknown possible effects on different organisms related. (Turner, 2007) There are also several other ethical issues raised, such as the monopoly of world food production by several ompanies, problems with intellectual property and non-mandatory labeling, which is the case in the United States. Non-mandatory labeling violates the rights of consumers to choose between ‘organic foods’ and genetically engineered foods. Monarch butterfly issue and Bt-Corn Several years ago, an issue was raised regarding how non-pest (non-targeted) species of organisms, the Monarch butterfly species in this case, were affected by the delta endotoxins contained in the pollen of a certain species of Bt-Corn. The issue revolves around how Monarch butterflies population was in danger of being killed through the poisoning by the Bt toxins.Monarch butterflies would migrate and lay their eggs on areas near the Bt-Corn fields. Their larvae feed on milkweed plants, a species of plants that grow in same regions as the Bt-Corn. However, Bt- Corn pollen would scatter throughout the area and lay on these leaves. Several investigations revealed some mortality in Monarch butterfly caterpillars that consume these pollen-covered milkweed leaves. (Peairs, 2007) Following the recent controversy, a number of private parties assembled and conducted workshops and investigations regarding this issue sponsored by the Agricultural Research Service (ARS) of the United States.Scientists and researchers were assembled from U. S. and Canadian universities, ARS members and several other environmental organizations, in a joint effort to prove whether the issue has a scientific basis. (Hellmich, 2008) Laboratory experiments done with pure Crystal toxins (Bt toxins) mixed with artificial diets revealed that a certain type of Cry toxin, Cry1Ab, was harmful to Monarch caterpillars but other types of the Cry toxins were not toxic to them.Field studies done along with lab experiments conclude that there were not any adverse effects observed on the Monarch caterpillars who fed on milkweed leaves dusted with natural levels of the commonly found Bt-Corn pollen species. All but the single Cry toxin proved to be safe. The results of this experiment caused for the termination of the production of Bt-Corn species 176, which expressed high amounts of Cry1Ab toxins. (Hellmich, 2008) Several other studies were conducted to compare between the mortality of Monarch caterpillars in agricultural and non-agricultural habitats, where there aren’t any Bt-Corn species in the area.Results from this experiment show no significant differences in mortality rates of the caterpillars. (Hellmich, 2008) Another study conducted compared the mortality rates of Monarch caterpillars exposed to Bt-Corn species and ‘organic’ corn species with the commonly used pesticide, cyhalothrin. Experimentations revealed how, â€Å"†¦nearly all monarch larvae on milkweed plants inside the field were killed. † Hence Bt-Corn is safer t han traditional commercial insecticides and pesticides. (Hellmich, 2008)The final risk assessment brought forth by Hellmich regarding the Monarch population and Bt-Corn is that the risks are negligible since exposure of the Monarch caterpillars to Bt-Corn pollen is low. Furthermore, the current commercially available Bt-Corn species and hybrids revealed low toxicity. Hellmich concludes that, â€Å"The bottom line from these studies is that all commercial Bt corn hybrids have negligible effects on populations of monarch butterflies, especially when compared with traditional insecticides. † (Hellmich, 2008) EvaluationIn conclusion, through research and investigations conducted by researchers across the world, we can see how the commercialization of Bt-Corn for past 14 years have significantly benefitted both society and the environment through the ability of farmers to cut down costs, usage of energy, fuel and CO2 emissions into the atmosphere, increase in yields and decrease i n the use of harmful chemicals such as pesticides and herbicides. We also see that most of the issues raised surrounding the issue of Bt-Corn and genetically engineered organisms are mostly just a matter of perspective and preferences.Lack of education and an open perspective regarding genetically modified organisms is the main hindrance towards improvements in the current agricultural field. Bibliography Aroian, R. (n. d. ). History of Bt. UCSD – Aroian Lab. Brookes, G. (2006, October). GM crops: the first ten years – Global socio-economic and environmental impacts. 1-106. Gertsberg, D. (2009, August 30). Introduction To The Regulation of Genetically Modified Foods by the FDA . Retrieved May 2, 2010, from GMO Journal: Food Safety Politics: http://gmo-journal. com/index. php/2009/08/30/introduction-to-regulation-of-gm-foods-by-fda/Hellmich, R. L. (2008, March 8). Monarch Butterflies and Bt Corn. 1-3. Hofte, H. (1989). Insecticidal Crystal Proteins of Bacilllus thuringi ensis. MICROBIOLOGICAL REVIEWS , 53, 242-255. James, C. (2002). Global Review of Commercialized Transgenic Crops: 2001. ISAAA Briefs (26), 1-184. Peairs, F. (2007, April). Bt Corn: Health and the Environment. Colorado State University Extension . Turner, L. (2007). Playing With Our Food. Better Nutrition , 69 (4), 30-33. Wu, F. (2006). Mycotoxin reduction in Bt corn: potential economic, health, and regulatory impacts . Transgenic Research , 277-289.

The Effects of Domestic Violence on Children Essay examples

Exposure to domestic violence can impact the behavioral, social-emotional, and cognitive development of children. Children who are exposed to domestic violence tend to exhibit more aggressive behaviors with their peers, show signs of depression, and have a difficult time forming relationships (Brown Bzostek, 2003). Cognitively, studies have shown that children exposed to domestic violence may have difficulties learning and concentrating in school, have difficulties with conflict resolution skills, and may believe in male privilege, (Brown Bzostek, 2003). Concentration is difficult for children exposed to domestic violence because of how unsafe they may feel in their surroundings. They may be preoccupied with the violence that is†¦show more content†¦Domestic violence also greatly impacts the family structure and the relationships between the members. Domestic violence threatens both the relationship between the child and their mother and the child and their father. Childre n who are exposed to domestic violence do not have an emotionally available parent to foster their development and have a 30-60% higher risk for being abused by the perpetrator (NCADV, 2007); when the father is the perpetrator of the violence, he often knows little about his children, their interests, and progress in school (Crosson-Tower, 2009, p. 84). The mother’s parenting style may also be damaged from domestic violence; the perpetrator may not allow the mother to take care of her children properly or soothe them when they are upset, which can cause the children to believe their mother does not care for them. When a mother is constantly traumatized by domestic violence, it can be more difficult for her to be present and attentive in her children’s lives due to depression, anxiety, and lack of sleep (Centre for children and families in the justice system, 2009). Domestic violence has an impact on the ability for a family to function. The perpetrator may sow division s between the members of the family by turning them against each other, or favoring one child over the others. There may also be role reversals in families who experience domestic violence; parentification of the children and infantilizing of the mother mayShow MoreRelatedThe Effects of Domestic Violence on Children1529 Words   |  7 PagesProject: The Effects of Domestic Violence on Children Trudy Root Kaplan University CM107-11 Children are negatively impacted by the surrounding of domestic violence in multiple ways, in which need to be identified. The audience that needs to be aware of domestic abuse’s effects on children is adults that care for children; such as pediatricians, teachers, counselors, and parents. 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